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神經病理性疼痛及轉譯醫學研究室

 

近五年學術著作

 

  1. Sing-Ong Lee, Li-Ping Huang, Chih-Shung Wong* (2020, Sep). Preoperative Administration of Extended-Release Dinalbuphine Sebacate Compares with Morphine for Post-Laparoscopic Cholecystectomy Pain Management: A Randomized Study. Journal of Pain Research, Volume 2020:13 Pages 2247—2253. 本人為通訊作者.
  2. Yu-Pin Feng, Tsorng-Shyang Yang, Chi-Hsiang Chung, Wu-Chien Chien, Chih-Shung Wong* (2020, Sep). Early childhood general anesthesia exposure associated with later developmental delay: A national population-based cohort study. PLOS ONE, 15(9):e0238289. 本人為通訊作者.
  3. Ing-Jung Chen, Chih-Ping Yang, Sheng-Hsiung Lin, Chang-Mei Lai and Chih-Shung Wong* (2020, Aug). The Circadian Hormone Melatonin Inhibits Morphine-Induced Tolerance and Inflammation via the Activation of Antioxidative Enzymes. Antioxidants, 2020, 9(9), 780. (SCIE, 7/61 (Q1) in 'Medicinal Chemistry'; 10/139 (Q1) in 'Food Science & Technology' and 56/297 (Q1) in 'Biochemistry & Molecular Biology'). MOST 107-2314-B-281-002-MY3. 本人為通訊作者. https://doi.org/10.3390/antiox9090780.
  4. Ing-Jung Chen and Chih-Shung Wong* (2020, Mar). Shea Nut Oil Extracts Enhance the Intra-Articular Sodium Hyaluronate Effectiveness on Surgically Induced OA Progression in Rats. Nutrients, 2020, 12(4), 957. (SCIE, 17/89 (Q1) in 'Nutrition & Dietetics'). 本人為通訊作者.
  5. Yaswanth Kuthati, Vaikar Navakanth Rao, Prabhakar Busa, Srikrishna Tummala, Goutham Davuluri Venkata Naga, and Chih Shung Wong* (2020, Mar). Scope and Applications of Nanomedicines for the Management of Neuropathic Pain. MOLECULAR PHARMACEUTICS, 2020, 17, 4, 1015–1027. (SCIE, 38/138, Q2, Medicine, Research & Experimental; 48/271, Q1, Pharmacology & Pharmacy). 本人為通訊作者.
  6. Yaswanth Kuthati, Prabhakar Busa, Venkata Naga Goutham Davuluri, Chih Shung Wong* (2019, Dec). Manganese Oxide Nanozymes Ameliorate Mechanical Allodynia in a Rat Model of Partial Sciatic Nerve-Transection Induced Neuropathic Pain. International Journal of Nanomedicine, 14:10105-10117. (SCIE, 24/271 (Q1) inPharmacology & Pharmacy). MOST 106-2314-B-281-003-MY3. 本人為通訊作者.
  7. Yu-Ching Chou, Chih-Hung Lin, Chih-Shung Wong, Wan-Yun Chou, Jin-Yin Chang, Chien-An Sun (2019, Dec). Statin use and the risk of renal cell carcinoma: national cohort study. Journal of Investigative Medicine, 68(3): 776-781.
  8. Hou-Chuan Lai, Meei-Shyuan Lee, Chin Lin, Kuen-Tze Lin, Yi-Hsuan Huang, Chih-Shung Wong, Shun-Ming Chan, Zhi-Fu Wu (2019, Aug). Propofol-based Total Intravenous Anaesthesia Is Associated With Better Survival Than Desflurane Anaesthesia in Hepatectomy for Hepatocellular Carcinoma: A Retrospective Cohort Study. British Journal of Anaesthesia, 123 (2), 151-160.
  9. Yaswanth Kuthati, Sheng-Hsiung Lin, Ing-Jung Chen, Chih-Shung Wong* (2019, Aug). Melatonin and their analogs as a potential use in the management of neuropathic pain. Journal of the Formosan Medical Association , 2019 Aug;118(8):1177-1186. (SCIE, 42/165 (Q2) in Medicine, General & Internal). MOST 106-2314-B-281-003-MY3. 本人為通訊作者.
  10. Yaswanth Kuthati, Venkata Naga Goutham Davuluri, Chih-Ping Yang, Hsiao-Cheng Chang, Chih-Peng Chang, Chih Shung Wong* (2019, Aug). Melatonin MT2 receptor agonist IIK-7 produces antinociception by modulation of ROS and suppression of spinal microglial activation in neuropathic pain rats. Journal of Pain Research, 2019(12):2473—2485. MOST 106-2314-B-281-003-MY3. 本人為通訊作者.
  11. Chih-Chung Liu, Hoong-Chien Lee, Yi-Shian Peng, Ailun Heather Tseng, Jia-Lin Wu, Wei-Yuan Tsai, Chih-Shung Wong*, Li-Jen Su* (2019, May). Transcriptome Analysis Reveals Novel Genes Associated with Cartilage Degeneration in Posttraumatic Osteoarthritis Progression. CARTILAGE, 2019 May 20:1947603519847744. 本人為通訊作者.
  12. Ing-Jung Chen, Sheng-Hsiung Lin, Chih-Shung Wong* (2019, Apr). Oral shea nut oil triterpene concentrate supplement ameliorates pain and histological assessment of articular cartilage deterioration in an ACLT injured rat knee osteoarthritis model. PLoS ONE, PLoS ONE 14(4): e0215812. 本人為通訊作者.
  13. Lin WL, Lee MS, Wong CS, Chan SM, Lai HC, Wu ZF, Lu CH. (2019, Mar). Effects of intraoperative propofol-based total intravenous anesthesia on postoperative pain in spine surgery: Comparison with desflurane anesthesia - a randomised trial.. Medicine (Baltimore), 2019 Mar;98(13):e15074..
  14. Yu-Che Cheng, Ru-Yin Tsai, Yen-Tseng Sung, Ing-Jung Chen, Tzu-Yi Tu, Ya-Yuan Mao, Chih-Shung Wong* (2018, Dec). Melatonin regulation of transcription in the reversal of morphine tolerance: Microarray analysis of differential gene expression. International Journal of Molecular Medicine, 2019 Feb;43(2):791-806. (SCIE, 71/139 (Q3) in medicine research & experimental). MOST 105-2314-B-281-003-MY2. 本人為通訊作者.
  15. Lai, H. C., Lu, C. H., Wong, C. S., Lin, B. F., Chan, S. M., Kuo, C. Y., & Wu, Z. F. (2018, Nov). Baicalein attenuates neuropathic pain and improves sciatic nerve function recovery in rats with partial sciatic nerve transection. J Chin Med Assoc, 81(11):955-963.
  16. Wu, Z. F., Lee, M. S., Wong, C. S., Lu, C. H., Huang, Y. S., Lin, K. T., . . . Lai, H. C. (2018, Nov). Propofol-based Total Intravenous Anesthesia Is Associated with Better Survival Than Desflurane Anesthesia in Colon Cancer Surgery. Anesthesiology, 129(5):932-941.
  17. Chang, C. L., Wong, C. S., Yang, Y. C., & Chiu, N. C. (2018, Apr). Influence of Latitude on the Prevalence of Kawasaki Disease: A Retrospective Cohort Study from the Taiwan National Health Insurance Database and Review of the Literature. Int J Environ Res Public Health, 25;15(5).
  18. Chan, S. M., Lin, B. F.,Wong, C. S., Chuang, W. T., Chou, Y. T., & Wu, Z. F. (2017, Aug). Levobuipivacaine-Induced Dissemination of A549 Lung Cancer Cells. Sci Rep, 7(1), 8646.
  19. Chun-Sung Sung, Zhi-Hong Wen, Chien-Wei Feng, Chun-Hong Chen, Shi-Ying Huang, Nan-Fu Chen, Wu-Fu Chen, Chih-Shung Wong* (2017, Jul). Potentiation of spinal glutamatergic response in the neuron-glia interactions underlies the intrathecal IL-1β-induced thermal hyperalgesia in rats. CNS Neuroscience & Therapeutics, 2017 Jul;23(7):580-589. (SCIE, 65/261 (Q1) in Pharmacology & Pharmacy). MOST 102-2314-B-075-024. 本人為通訊作者.
  20. Jia-Lin Wu , Wei-Yuan Tsai , Jian-Horng Chen , Chih-Shung Wong* (2017, Mar). Dextromethorphan upregulates osteoblast and osteoclast activity but does not attenuate ovariectomy-induced osteoporosis. Life Sciences, 15;173:145-149. 本人為通訊作者.
  21. Sheng-Hsiung Lin, Ting-Chuan Wang, Chun-Fu Lai, Ru-Yin Tsai, Chih-Ping Yang, Chih-Shung Wong* (2017, Mar). Association of anterior cruciate ligament injury with knee osteoarthritis and total knee replacement: A retrospective cohort study from the Taiwan National Health Insurance Database. PLOS one, 2017 May 30;12(5):e0178292.. 本人為通訊作者.
  22. Jen-Hsin Kao, Sheng-Hsiung Lin, Chun-Fu Lai, Yu-Chieh Lin, Zwe-Ling Kong, Chih-Shung Wong* (2016, Sep). Shea Nut Oil Triterpene Concentrate Attenuates Knee Osteoarthritis Development in Rats: Evidence from Knee Joint Histology. . PLOS One, 2016; 11(9): e0162022.. 本人為通訊作者.
  23. Wei-Yuan Tsai, Ru-Yin Tsai, Chih-Chung Liu, Jia-lin Wu, Chih-Shung Wong* (2016, Apr). Sulfasalazine Attenuates ACL Transection and Medial Menisectomy-Induced Cartilage Destruction by Inhibition of Cystine/Glutamate Antiporter. Journal of Orthopaedic Research, 2016 Apr;34(4):650-7. (Accepted). 本人為通訊作者.

 

執行中研究計畫:

 

109年度行政院科技部

計畫名稱:晝夜節律與疼痛:脊髓褪黑激素在嗎啡耐受性之角色

計畫編號:MOST 107-2314-B-281-002-MY3

核定金額:壹佰貳拾柒萬陸仟元整

計畫時程:109/08/01-110/07/31

 

109年度-(產學合作天義)-院外研究計畫

計劃名稱:以標準膝骨關節炎動物模型評估保健食品關立固對骨關節炎之保健效果

核定金額:壹佰叁拾玖萬捌仟伍佰壹拾捌元整

執行期間:109/02/20~110/02/19

 

109年度國泰綜合醫院(院內計畫)

計畫名稱:類鴉片藥物遞送系統:聚多巴胺奈米載體之建立與檢測

計畫編號:CGH-MR-A10905

核定金額:伍拾萬元整

計畫時程:109/07/01~110/06/30

 

109年度國泰綜合醫院(院內計畫)

計畫名稱:乳木果油萃取物在大鼠關節炎模型下之保護效果: 分子機制與生物標記物探討

計畫編號:CGH-MR-A10913

核定金額:伍拾萬元整

計畫時程:109/11/01~110/10/30

 

109年度三軍總醫院民診基金醫學研究發展(黃𤦬慈醫師)

計畫名稱:大鼠嗎啡與皮下納疼解之間鎮痛作用的研究

計畫編號:TSGH-D-109193

核定金額:貳拾貳萬貳仟捌佰參拾肆元整

計畫時程:109/01/01-109/12/31

 

110年度三軍總醫院民診基金醫學研究發展(黃𤦬慈醫師)

計畫名稱:大鼠納疼解對嗎啡鎮痛耐受性的影響

計畫編號:TSGH-D-110158

核定金額:貳拾參萬玖仟元整

計畫時程:110/01/01-110/12/31

 


更新時間:2021/3/16