Yen BL, Huang HI, Chien CC, Jui HY, Ko BS, Yao M, Shun CT, Yen ML, Lee MC, Chen YC: Isolation of multipotent cells from the human term placenta. Stem Cells, 2005; 23:3-9. (SCI, Impact Factor: 7.871; [Biotechnology & Applied Microbiology] Ranking: 8/160)
Yang SH*, Chien CC*, Chen CW, Li SY and Huang CJ: Potential of fecal RNA in diagnosing colorectal cancer. Cancer Letters, 2005; 226:55-63. (SCI, Impact Factor: 4.864; [Oncology] Ranking: 33/184) *Contributed equally
Tsai YF, Wei SL, Lin YP, and Chien CC: Depressive symptoms, pain experiences, and pain management strategies among residents of Taiwanese public elder care homes. Journal of Pain and Symptom Management, 2005, 30:63–69. (SCI, Impact Factor: 2.640; [Health care sciences & services] Ranking: 9/71)
Chien CC, Yen BL, Lee FK, Lai TH, Chen YC, Chan SH, Huang HI: In vitro differentiation of human placenta-derived multipotent cells into hepatocyte-like cells. Stem Cells, 2006, 24:1759-1768. (SCI, Impact Factor: 7.871; [Biotechnology & Applied Microbiology] Ranking: 8/160)
Chien CC, Chang CC, Yang SH, Chen SH, Huang CJ: A homologue of the Drosophila headcase protein, HECA, is a novel tumor marker for early-stage colorectal cancer. Oncology Reports, 2006, 15(4):919-926. (SCI, Impact Factor:1.686; [Oncology] Ranking: 134/184)
Chang CJ, Yen ML, Chen YC, Chien CC, Huang HI, Bai CH, Yen BL: Placenta-Derived Multipotent Cells Exhibit Immunosuppressive Properties That Are Enhanced in the Presence of Interferon-. Stem Cells, 2006, 24:2466-2477. (SCI, Impact Factor: 7.871; [Biotechnology & Applied Microbiology] Ranking: 8/160)
Chien CC, Fu WM, Huang HI, Lai YH, Tsai YF, Guo SL, Wu TJ, Ling QD: Expression of Neurotrophic Factors in Neonatal Rats After Peripheral Inflammation. Journal of Pain, 2007, 8(2):161-167. (SCI, Impact Factor: 4.851; [Clinical Neurology] Ranking: 21/185)
Chien CC, Chen SH, Liu CC, Lee CL, Yang RN, Yang SH, Huang CJ: Correlation of K-ras codon 12 mutations in human feces and ages of patients with colorectal cancer. Translational Research (Journal of Laboratory Clinical Medicine), 2007, 149:96-102. (SCI, Impact Factor: 2.903; [Medical Laboratory Technology] Ranking: 5/30)
Tsai, FC, Tsai, YF, Chien, CC, Lin, CC: Emergency nurses' knowledge of perceived barriers in pain management in Taiwan. Journal of Clinical Nursing, 2007, 16(11):2088-95. (SCI, Impact Factor: 1.226; [Nursing] Ranking: 26/88)
Yen ML, Chien CC, Chiu IM, Huang HI, Chen YC, Hu HI, Yen BL: Multilineage differentiation and characterization of the human fetal osteoblastic 1.19 cell line: a possible in vitro model of human mesenchymal progenitors. Stem Cells, 2007, 25:125-131. (SCI, Impact Factor: 7.871; [Biotechnology & Applied Microbiology] Ranking: 8/160)
Huang JS, Huang CJ, Chen SK, Chien CC, Chen CW, and Lin CM: Associations between VHLngenotype and clinical phenotype in familial von Hippel-Lindau disease. European Journal of Clinical Investigation, 2007, 37(6):492-500 (SCI, Impact Factor: 2.736; [Medicine, General & Internal] Ranking: 26/151)
Yen BL*, Chien CC*, Chen YC, Chen JT, Huang JS, Lee FK, Huang HI: Placenta-derived multipotent cells differentiate into neuronal and glial cells in vitro. Tissue Engineering: Part A, 2008, 14(1):9-17 (SCI, Impact Factor: 4.636; [Biotechnology & Applied Microbiology] Ranking: 20/160) *Contributed equally
Chien CC: Clinical trial registration – now and thereafter. Acta Anaesthesiologica Taiwanica 2008, 46(2):55-56.
Huang CJ, Chien CC, Yang SH, Chang CC, Sun HL, Chen SH, Liu CC, Lin CM: Fecal ribosomal protein L19 is a genetic prognostic factor for survival in colorectal cancer. Journal of Cellular & Molecular Medicine, 2008, 12(5B):1936-1943 (SCI, impact factor: 4.608; [Medicine, Research & Experimental] Ranking: 18/106)
Guo SL, Ling QD, Huang HI, Chien CC, Li MJ, Wu TJ, and Cheng YC: CSF protein profiling by Surface-Enhanced Laser Desorption/Ionization Time-of Flight Mass Spectrometry after Depletion of Albumin and IgGs. The Chinese Journal of Pain 2008, 18(1):7-14.
Sun HL, Cheng YC, Guo SL, Chien CC, Tzeng JI, Chien LH, and Ling QD: Identification of genes expression in spinal cord after peripheral inflammation using DNA microarray techniques. The Chinese Journal of Pain 2008, 18(1):15-24.
Chang CC, Chien CC, Yang SH, Chen SH, Huang CJ: Identification and clinical correlation of decreased expression of cytoplasmic dynein heavy chain 1 in patients with colorectal cancer. Clinical Molecular Medicine, 2008, 1 (1):6-10.
Wu CC, Chao YC, Chen CN, Chien S, Chen YC, Chien CC, Chiu JJ, Linju Yen B: Synergism of biochemical and mechanical stimuli in the differentiation of human placenta-derived multipotent cells into endothelial cells. Journal of Biomechanics, 2008, 41(4):813-21. (SCI, Impact Factor: 2.463; [Engineering, Biomedical ] Ranking: 18/69)
Yang C, Huang CH, Cheong ML, Hung KL, Lin LH, Yu YS, Chien CC, Huang HC, Chen CW and Huang CJ: Unambiguous molecular detections with multiple genetic approach for the complicated chromosome 22q11 deletion syndrome. BMC Medical Genetics, 2009, 10:16-23. (SCI, Impact Factor: 2.439; [Genetics & Heredity ] Ranking: 84/156)
Sun HL, Wu TZ, Ng CC, Chien CC, Huang CC, Chie WC: Efficacy of oropharyngeal lidocaine instillation on hemodynamic responses to orotracheal intubation. Journal of Clinical Anesthesia, 2009, 21:103-107. (SCI, Impact Factor: 1.279; [Anesthesiology] Ranking: 18/26)
Huang JS, Lin CM, Cheng YC, Hung KL, Chien CC, Chen SK, Chang CJ, Chen CW, Huang CJ: A vitronectin M381T polymorphism increases risk of hemangioblastoma in patients with VHL gene defect. Journal of Molecular Medicine - JMM, 2009, published online. (SCI, Impact Factor: 5.192; [Medicine, Research & Experimental] Ranking: 13/106)
Wang YJ, Wang YC, Chien CC, Chen CJ, Yang RN, Fang CL: Diagnosis of hepatic angiomyolipomata using CT: report of three cases and review of the literature. Clinical Radiology, 2009, 64(3):329-34. (SCI, Impact Factor: 1.765; [Radiology, Nuclear Medicine & Medical Imaging] Ranking: 60/111)
Guo SL, Wu TJ, Liu CC, Ng CC, Chien CC, Sun HL: Meperidine-induced serotonin syndrome in a susceptible patient. British Journal of Anaesthesia, 2009, 103(3):369-70. (SCI, Impact Factor: 4.224; [Anesthesiology] Ranking: 3/26)
Chang CC, Yang SH, Chien CC, Chen SH, Pan S, Lee CL, Lin CM, Sun HL, Huang CC, Wu YY, Yang RN, Huang CJ: Clinical meaning of age-related expression of fecal cytokeratin 19 in colorectal malignancy. BMC Cancer, 2009, 9: 976-83. (SCI, Impact Factor: 3.153; [Oncology] Ranking: 66/184)
Huang HI, Cheng YC, Chen WY, Tsao CW, Huang CJ, Liu HT, Chien CC #: Comparative proteomic analysis of Placenta-Derived Multipotent Cells (PDMCs) and its differentiated Neuron. The Chinese Journal of Pain 2010, 20(1):1-11. #Correspondence
Tsao SY, Hsu HC, Guo SL, Wang TC, Chien CC#: Risk factors for the development of neuropathic pain in type 2 DM patients.? The Chinese Journal of Pain 2010, Accepted. #Correspondence
Liu CC, Yeh YC, Sun HL, Lee YH, Chien CC, Wong CS: The treatment of pain benefits the treatment of insomnia. The Chinese Journal of Pain 2010, Accepted.
Liu CC, Sun HL, Lee YH, Chien CC, Ho ST: Neuroaxial Anesthesia does not Increase the Incidence of Post- operative Low Back Pain in Adult Patients Receiving Herniorrhaphy. The Chinese Journal of Pain 2010, Accepted.
Cheng YC, Lee YC, Huang CJ, Han CT, Chien CC#: Cytoskeleton proteomic changes in the process of Placenta-Derived Multipotent Cells (PDMCs) differentiated into Neuron. Fu-Jen Journal of Medicine, 2010, 8(1)1-8. #Correspondence
LT Tien*, Chien CC*, Yang SH, Lin CM, Wu YY, Huang CJ: p53-dependent expression of ribosomal protein S27-like in colorectal cancer. Fu-Jen Journal of Medicine, 2010, 8(1):9-16. *Contributed equally
Kim FJ, Kovalyshyn I, Burgman M, Neilan C, Chien CC, Pasternak GW: Sigma 1 receptor modulation of G-protein-coupled receptor signaling: potentiation of opioid transduction independent from receptor binding. Molecular Pharmacology, 2010, 77(4): 695-703. (SCI, Impact Factor: 4.725; [Pharmacology & Pharmacy] Ranking: 23/249)
Yang SH, Huang CJ, Lee CL, Liu CC, Chien CC, Chen SH: Fecal RNA detection of cytokeratin 19 and ribosomal protein L19 for colorectal cancer. Hepato-Gastroenterology, 2010, 57(101):710-5, Jul-Aug. (SCI, Impact Factor: 0.677; [Surgery] Ranking: 142/187)
Lin PH, Kao YH, Chang Y, Cheng YC, Chien CC, Chen WY: Daunomycin interaction with DNA: microcalorimetric studies of the thermodynamics and binding mechanism. Journal of Biotechnology, 2010, 5(10):1069-77, Oct. (SCI, Impact Factor: 2.970; [Biotechnology & Applied Microbiology] Ranking: 49/160)
Yang RN, Yang SH, Chang CC, Chien CC, Pan S, Huang CJ: Upregulation of fecal cytokeratin 19 is associated with prognosis in older colorectal cancer patients. Genetic Testing & Molecular Biomarkers, 2010, 14(5):703-8, Oct. (SCI, Impact Factor:0.879; [Genetics & Heredity] Ranking: 135/156)
Lin JY, Cheng YC, Chen JY, Chien CC, Lin SC, Wen YR, Tsou TS, Ling QD: Increased spinal prodynorphin gene expression in reinflammation-associated hyperalgesia after neonatal inflammatory insult. BMC Neuroscience, 2010, 11:139 (SCI, Impact Factor: 3.091; [Neuroscience] Ranking: 100/237)
Lee SO, Li MJ, Ho HM, Chien CC, Guo SL: Perioperative transient ischemic attack caused by the cessation of warfarin. Acta Anaesthesiologica Taiwanica, 2010, 48(4):188-90, Dec.
Shen CH, Tsai RY, Shih MS, Lin SL, Tai YH, Chien CC, Wong CS: Etanercept restores the antinociceptive effect of morphine and suppresses spinal neuroinflammation in morphine-tolerant rats. Anesthesia & Analgesia, 2011, 112(2):454-9, Feb. (SCI, Impact Factor: 3.274; [Anesthesiology] Ranking: 5/26)
Chen WY, Huang JT, Cheng YC, Chien CC, Tsao CW: Fabrication of nanostructured silicon by metal-assisted etching and its effects on matrix-free laser desorption/ionization mass spectrometry. Analytica Chimica Acta, 2011, 687(2): 97-104, Feb 21. (SCI, Impact Factor: 3.757; [Chemistry, Analytical] Ranking: 5/70)
Chien CC: Genetics in pain management. Acta Anaesthesiologica Taiwanica 2011, 49(1):1-2, Mar.
Huang CJ, Yang SH, Huang SM, Lin CM, Chien CC, Chen YC, Lee CL, Wu HH, Chang CC: A predicted protein, KIAA0247, is a cell cycle modulator in colorectal cancer cells under 5-FU treatment. Journal of Translational Medicine, 2011, 9:82, May. (SCI, Impact Factor: 3.508; [Medicine, Research & Experimental] Ranking: 27/106)
Shen CH, Tsai RY, Tai YH, Lin SL, Chien CC, Wong CS: Intrathecal etanercept partially restores morphine's antinociception in morphine-tolerant rats via attenuation of the glutamatergic transmission. Anesthesia & Analgesia, 2011, 113(1):184-90, Jul. (SCI, Impact Factor: 3.274; [Anesthesiology] Ranking: 5/26)
Chien CC, Tien LT, Huang CJ, Yang SH, and Lee CL: Lowly Expressed Ribosomal Protein S19 in the Feces of Patients with Colorectal Cancer. ISRN Gastroenterology, 2012, doi:10.5402/2012/394545
Huang YN, Tsai RY, Lin SL, Chien CC, Cherng CH, Wu CT, Yeh CC, Wong CS: Amitriptyline attenuates astrocyte activation and morphine tolerance in rats: role of the PSD-95/NR1/nNOS/PKCgamma signaling pathway. Behavioural Brain Research, 2012, 229(2):401-11, Apr 15. (SCI, Impact Factor: 3.391; [Behavioural Sciences] Ranking: 14/49)
Chien CC, Lee YJ, Fan LW, Ho IK, Tien LT: Naloxonazine, a specific mu-opioid receptor antagonist, attenuates the increment of locomotor activity induced by acute methamphetamine in mice. Toxicology Letters, 2012, 212(1):61-5, 2012 Jul 7. (SCI, Impact Factor: 3.355; [Toxicology] Ranking: 20/87)
Lin YS, Tsai RY, Shen CH, Chien CC, Tsai WY, Guo SL, Wong CS: Ultra-low dose naloxone restores the antinocicepitve effect of morphine in PTX-treated rats: association of IL-10 upregulation in the spinal cord. Life Sciences, 2012, 91(5-6):213-20, 2012 Sep 4. (SCI, Impact Factor: 2.296; [Pharmacology & Pharmacy] Ranking: 124/254)
Cheng YC, Chen KH, Wang JS, Hsu WL, Chien CC, Chen WY, Tsao CW: Rapid analysis of abused drugs using nanostructured silicon surface assisted laser desorption/ionization mass spectrometry. Analyst, 2012,137(3):654-61, Feb 7. (SCI, Impact Factor: 3.906)
Tsao CW, Lin CH, Cheng YC, Chien CC, Chang CC, Chen WY: Nanostructured silicon surface modifications for as a selective matrix-free laser desorption/ionization mass spectrometry. Analyst, 2012, 137(11):2643-50, 2012 Jun 7. (SCI, Impact Factor: 3.906)
Huang CJ, Yang SH, Lee CL, Cheng YC, Tai SY, Chien CC*: Ribosomal Protein S27-Like in Colorectal Cancer: a Candidate for Predicting Prognoses. PLoS One, 2013, 8(6): e67043, doi: 10.1371/journal.pone.0067043. (SCI, Impact Factor: 3.534; [MULTIDISCIPLINARY SCIENCES] Ranking: 8/55 (14.55%)) *Correspondence
Huang CJ, Teng HW, Chien CC, Lin JK, Yang SH: Prognostic Significance of C-Reactive Protein Polymorphism and KRAS/BRAF in Synchronous Liver Metastasis from Colorectal Cancer. PLoS One, 2013, 8(6): e65117, doi: 10.1371/journal.pone.0065117. (SCI, Impact Factor: 3.534; [MULTIDISCIPLINARY SCIENCES] Ranking: 8/55 (14.55%))
Hu WW, Chen YJ, Ruaan RC, Chen WY, Cheng YC, Chien CC: The regulation of DNA adsorption and release through chitosan multilayers. Carbohydrate Polymers, 2014, 99: 394-402. (SCI, Impact Factor: 3.916)
Hu WW, Hsu YT, Cheng YC, Li C, Ruaan RC, Chien CC, Chung CA, Tsao CW: Electrical stimulation to promote osteogenesis using conductive polypyrrole films. Materials Science and Engineering: C, 2014, 37: 28-36. (SCI, Impact Factor: 2.736)
Cheng CC, Chung CA, Su LC, Chien CC*,#, Cheng YC*,#: Osteogenic differentiation of placenta-derived multipotent cells (PDMCs) in vitro. #Contributed equally; *Correspondence. Taiwanese Journal of Obstetrics & Gynecology, 2014, 53:187-192. (SCI, Impact Factor: 1.261; [Obsterics & Gynecolog] Ranking: 57/78, JCR2013).
Chen SK, Chung CA, Cheng YC, Huang CJ, Ruaan RC, Chen WY, Li C, Tsao CW, Hu WW, Chien CC*: Hydrostatic pressure enhances mitomycin C- induced apoptosis in urothelial carcinoma cells. Urologic Oncology - Seminars and Original Investigations, 2014, 32, 26.e17–26.e24. (SCI, Impact Factor: 3.363; [Urology & Nephrology] Ranking: 14/75(18.67%)) *Correspondence.
Chen SK, Chung CA, Cheng YC, Huang CJ, Chen WY, Ruaan RC, Li C, Tsao CW, Hu WW, and Chien CC*: Toll-Like Receptor 6 and Connective Tissue Growth Factor Are Significantly Upregulated in Mitomycin-C-Treated Urothelial Carcinoma Cells Under Hydrostatic Pressure Stimulation. Genetic Testing and Molecular Biomarkers. 2014, 18, 6: 410-416. (SCI, Impact Factor:1.147; [Genetics & Heredity] Ranking: 142/164) *Correspondence.
Cheng YC, Tsao CW, Chiang MZ, Chung CA, Chien CC, Hu WW, Ruaan RC, and Li C: Microfluidic platform for human placenta-derived multipotent stem cells culture and applied for enhanced neuronal differentiation. Microfluidics and Nanofluidics, 2015, 18, 4: 587–598 (SCI, Impact Factor: 2.344)
Yeh CC, Sun HL, Huang CJ, Wong CS, Cherng CH, Huh BK, Wang JS,* and Chien CC*: Long-Term Anti-Allodynic Effect of Immediate Pulsed Radiofrequency Modulation through Down-Regulation of Insulin-Like Growth Factor 2 in a Neuropathic Pain Model. Int. J. Mol. Sci. 2015, 16(11), 27156-27170; doi:10.3390/ijms161126013 (SCI, Impact Factor:3.226) *Co-correspondence
Cheng YC, Huang CJ, Lee YJ, Tien LT, Ku WC, Chien R, Lee FK, and Chien CC*: Knocking down of heat-shock protein 27 directs differentiation of functional glutamatergic neurons from placenta-derived multipotent cells. Sci Rep. 2016; 6: 32907. doi: 10.1038/srep32907 (SCI, Impact Factor:5.228) *Co-correspondence
Yeh CC, Wu ZF, Chen CH, Wong CS, Huang CJ, Wang JS, and Chien CC*: Association between extracellular signal-regulated kinase expression and the anti-allodynic effect in rats with spared nerve injury by applying immediate pulsed radiofrequency. BMC Anesthesiology. 2015, 15:92 https://doi.org/10.1186/s12871-015-0071-3 (SCI, Impact Factor: 1.525) *Co-correspondence
Chang CC, Huang CC, Yang SH, Chien CC, Lee CL, and Huang CJ: Data on clinical significance of GAS2 in colorectal cancer cells. Data in Brief. 2016, 8, 82-86
Han SL, Xie MJ, Chien CC, Cheng YC and Tsao CW: Using MEMS-based inertial sensor with ankle foot orthosis for telerehabilitation and its clinical evaluation in brain injuries and total knee replacement patients. Microsystem Technologies. 2016, 22:3, 625–634 (SCI, Impact Factor: 1.195)
Lee CL, Huang CJ, Yang SH, Chang CC, Huang CC, Chien CC, and Yang RN: Discovery of genes from feces correlated with colorectal cancer progression. Oncology Letters, 2016, 12:5, 3378-3384. https://doi.org/10.3892/ol.2016.5069. (SCI, Impact Factor:1.39; [Oncology] Ranking: 68/217)
Huang CJ, Huang SH, Chien CC, Lee HH, Yang SH, Chang CC, and Lee CL: Impact of microsatellite status on chemotherapy for colorectal cancer patients with KRAS or BRAF mutation. Oncology Letters, 2016, 12:6, 4427-4434. https://doi.org/10.3892/ol.2016.5275. (SCI, Impact Factor:1.39; [Oncology] Ranking: 68/217)
Huang CJ, Lee CL, Yang SH, Chien CC, Huang CC, Yang RN, and Chang CC: Upregulation of the growth arrest-specific-2 in recurrent colorectal cancers, and its susceptibility to chemotherapy in a model cell system. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2016, 1862(7): 1345-1353. (SCI, Impact Factor: 5.476)
HuangCJ, Lee CL, Liu CY, Huang SH, Hou JW, Chen YH, Chien CC, Ho CH, Lo WC, Hung KL: Detection of lower levels of SNAP25 using multiple microarray systems and its functional significance in medulloblastoma. International Journal of Molecular Medicine, 2017, 39(5): 1195-1205, https://doi.org/10.3892/ijmm.2017.2925 (SCI, Impact Factor:2.341; [Medicine Research and Experimental] Ranking: 21/128)
Chien CC, Huang CJ, Tien LT, Cheng YC, Ke CY, and Lee YJ: Suppression of HSP27 Restores Retinal Function and Protects Photoreceptors From Apoptosis in a Light-Induced Retinal Degeneration Animal Model. Investigative Ophthalmology & Visual Science, 2017, 58: 3107-3117. doi:10.1167/iovs.16-21007. (SCI, Impact Factor: 3.303)
Chien CC, Cai YJ, Tien LT, Lee YJ: Subretinal Transplantation of Human Amniotic Membrane Mesenchymal Stem Cell Restores Retinal Function Loss on Light-induced Retinopathy. Fu-Jen Journal of Medicine, 2017, 15:2, 59-78. DOI 10.3966/181020932017061502001
Huang CJ, Lee FK, Chen SK, Chien CC, Wu ST, and Wang YC: Clinical significance of interleukin‑6 and inducible nitric oxide synthase in ketamine‑induced cystitis. International Journal of Molecular Medicine, 2017, DOI: 10.3892/ijmm.2017.3264. (SCI, Impact Factor:2.341; [Medicine Research and Experimental] Ranking: 21/128)
Lin ST, Chen SK, Guo JW, Su IC, Huang CJ, Chien CC, Chang CJ: (2018, Nov). Dynamic expression of SMAD3 is critical in osteoblast differentiation of PDMCs. International Journal of Molecular Medicine, Published online on: November 26, 2018 https://doi.org/10.3892/ijmm.2018.4001.
Chien CC, Lim YT, Tien LT, Lee YJ: (2018, Feb). Subretinal-transplanted Umbilical Mesenchymal Stem Cells Express Retinal Cell Markers and Reverse Retinal Function Loss in a Light-induced Retinopathy Model. Fu-Jen Journal of Medicine, Vol.16 No.1 p1-15.
Issued by The Unites States of America: Chen YC, Yen LJ, Chien CC, Huang HI: Placental stem cell and methods thereof, US Patent No: US 7,534,606 B2, Date of patent: May 19, 2009
Issued by Taiwan, R.O.C.: Placenta-derived multipotent stem cells and the method for their isolation and preparation, R.O.C. Patent No: I299752, Date of patent: Aug. 11, 2008
Issued by Taiwan, R.O.C.: Guanidinium thiocyanate buffers enabling to purify human fecal total RNA, R.O.C. Patent No: I306474, Date of patent: Feb. 21, 2009
Issued by Taiwan, R.O.C.: Method of isolation and purification of RNA molecules from stool, R.O.C. Patent No: I306475, Date of patent: Feb. 21, 2009
Issued by Taiwan, R.O.C.: A method for the preparation of Placenta-derived multipotent stem cells, R.O.C. Patent No: I307717, Date of patent: Mar. 21, 2009