科主任：莊文郁

論文及學術著作

A.Journal Articles

• Chao YK, Wen YW, Chuang WY, Cerfolio RJ. Transition from video-assisted thoracoscopic to robotic esophagectomy: a single surgeon's experience. Dis Esophagus 2020; 33(2): doz033. (SCI)
• Chung IC, Chen LC, Tsang NM, Chuang WY, Liao TC, Yuan SN, OuYang CN, Ojcius DM, Wu CC, Chang YS. Mitochondrial Oxidative Phosphorylation Complex Regulates NLRP3 Inflammasome Activation and Predicts Patient Survival in Nasopharyngeal Carcinoma. Mol Cell Proteomics 2020; 19(1): 142-154. (SCI)
• Chuang WY, Chang ST, Yuan CT, Chang GJ, Chang H, Yeh CJ, Ueng SH, Kao HW, Wang TH, Wan YL, Shih LY, Chuang SS, Hsueh C. Identification of CD5/cyclin D1 Double-negative Pleomorphic Mantle Cell Lymphoma: A Clinicopathologic, Genetic and Gene Expression Study. Am J Surg Pathol 2020; 44(2): 232-240. (SCI)
• Tsai CL, Chang JS, Yu MC, Lee CH, Chen TC, Chuang WY, Kuo WL, Lin CC, Lin SM, Hsieh SY. Functional Genomics Identifies Hepatitis-Induced STAT3-TYRO3-STAT3 Signaling as a Potential Therapeutic Target of Hepatoma. Clin Cancer Res 2020; 26(5): 1185-1197. (SCI)
• Lin GW, Xu C, Chen K, Huang HQ, Chen J, Song B, Chan JKC, Li W, Liu W, Shih LY, Chuang WY, Kim WS, Tan W, Peng RJ, Laurensia Y, Cheah DMZ, Huang D, Cheng CL, Su YJ, Tan SY, Ng SB, Tang TPL, Han K, Wang VY, Jia WH, Pei Z, Li YJ, Gao S, Shi Y, Hu Z, Zhang F, Zhang B, Zeng YX, Shen H, He L, Ong CK, Lim ST, Chanock S, Kwong YL, Lin D, Rothman N, Khor CC, Lan Q, Bei JX; International NKTCL Working Group. Genetic risk of extranodal natural killer T-cell lymphoma: a genome-wide association study in multiple populations. Lancet Oncol 2020; 21(2): 306-316. (SCI)
• Chuang WY, Chang SH, Yu WH, Yang CK, Yeh CJ, Ueng SH, Liu YJ, Chen TD, Chen KH, Hsieh YY, Hsia Y, Wang TH, Hsueh C, Kuo CF, Yeh CY. Successful Identification of Nasopharyngeal Carcinoma in Nasopharyngeal Biopsies Using Deep Learning. Cancers 2020; 12(2): 507. (SCI)
• Chen CY, Chen CC, Chuang WY, Leu YL, Ueng SH, Hsueh C, Yeh CT, Wang TH. Hydroxygenkwanin Inhibits Class I HDAC Expression and Synergistically Enhances the Antitumor Activity of Sorafenib in Liver Cancer Cells. Front Oncol 2020; 10: 216. (SCI)
• Lin YC, Chuang WY, Wei FC, Yeh CH, Tinhofer I, Al Deek NF, Fu TC, Ng SC, Chang TC, Cheung YC, Ng SH, Juan YH. Peripheral arterial disease: the role of extracellular volume measurements in lower limb muscles with MRI. Eur Radiol 2020; 30(7): 3943-3950. (SCI)
• Wang TH, Wu CC, Huang KY, Chuang WY, Hsueh C, Li HJ, Chen CY. Profiling of subcellular EGFR interactome reveals hnRNP A3 modulates nuclear EGFR localization. Oncogenesis 2020; 9(4): 40. (SCI)
• Chen SL, Huang SF, Ho VW, Chuang WY, Chan KC. Clinical characteristics and treatment outcome of adenoid cystic carcinoma in the external auditory canal. Biomed J 2020; 43(2): 189-194. (SCI)
• Wan YL, Wu PW, Huang PC, Tsay PK, Pan KT, Trang NN, Chuang WY, Wu CY, Lo SB. The Use of Artificial Intelligence in the Differentiation of Malignant and Benign Lung Nodules on Computed Tomograms Proven by Surgical Pathology. Cancers 2020; 12(8): 2211. (SCI)
• Chen CY, Fang JY, Chen CC, Chuang WY, Leu YL, Ueng SH, Wei LS, Cheng SF, Hsueh C, Wang TH. 2-O-Methylmagnolol, a Magnolol Derivative, Suppresses Hepatocellular Carcinoma Progression via Inhibiting Class I Histone Deacetylase Expression. Front Oncol 2020; 10: 1319. (SCI)
• Lai YC, Juan YH, Ng SH, Lo TC, Chuang WY, Chen CC, Liau CT, Lin G, Lin YJ, Lin YC. Simple Stepwise Approach to Differentiate Cyst-Like Soft-Tissue Masses by Using Time-Resolved Magnetic Resonance Angiography. Diagnostics 2020; 10(12): 1094. (SCI)
• Lin CH, Anggelia MR, Cheng HY, Wang AYL, Chuang WY, Lin CH, Lee WPA, Wei FC, Brandacher G. The intragraft vascularized bone marrow component plays a critical role in tolerance induction after reconstructive transplantation. Cell Mol Immunol 2021; 18(2): 363-373. (SCI)
• Anggelia MR, Cheng HY, Chuang WY, Hsieh YH, Wang AYL, Lin CH, Wei FC, Brandacher G, Lin CH. Unraveling the Crucial Roles of FoxP3+ Regulatory T Cells in Vascularized Composite Allograft Tolerance Induction and Maintenance. Transplantation 2021; 105(6): 1238-1249. (SCI)
• Chao YK, Tsai CY, Illias AM, Chen CY, Chiu CH, Chuang WY. A standardized procedure for upper mediastinal lymph node dissection improves the safety and efficacy of robotic McKeown oesophagectomy. Int J Med Robot 2021; 17(3): e2244. (SCI)
• Tu KH, Fan PY, Chen TD, Chuang WY, Wu CY, Ku CL, Tian YC, Yang CW, Fang JT, Yang HY. TAFRO Syndrome with Renal Thrombotic Microangiopathy: Insights into the Molecular Mechanism and Treatment Opportunities. Int J Mol Sci 2021; 22(12): 6286. (SCI)
• Ong SY, Lim JQ, Grigoropoulos N, Laurensia Y, Huang D, Chia BKH, Zhe DCM, Saraf SA, Cheng CL, Chuang WY, Kuo MC, Su YJ, Phipps C, Nagarajan C, Lee YS, Lung DTC, Shih LY, Goh YT, Lim ST, Ong CK. No association between ECSIT germline mutations and hemophagocytic lymphohistiocytosis in natural killer/T-cell lymphoma. Haematologica 2021; 106(6): 1737-1739. (SCI)
• Chang H, Chuang WY. Evolution of 18F-FDG Uptake as a Pitfall of Image Diagnosis for Systemic Anaplastic Large Cell Lymphoma. Diagnostics 2021; 11(8): 1387. (SCI)
• Ong YC, Kao HW, Chuang WY, Hung YS, Lin TL, Chang H, Kuo MC. Intravascular Large B-cell lymphoma: A case series and review of literatures. Biomed J 2021; 44(4): 479-488. (SCI)
• Hsu WC, Huang PC, Pan KT, Chuang WY, Wu CY, Wong HF, Yang CT, Wan YL. Predictors of Invasive Adenocarcinomas among Pure Ground-Glass Nodules Less Than 2 cm in Diameter. Cancers 2021; 13(16): 3945. (SCI)
• Chen CC, Chen CY, Cheng SF, Shieh TM, Leu YL, Chuang WY, Liu KT, Ueng SH, Shih YH, Chou LF, Wang TH. Hydroxygenkwanin Increases the Sensitivity of Liver Cancer Cells to Chemotherapy by Inhibiting DNA Damage Response in Mouse Xenograft Models. Int J Mol Sci 2021; 22(18): 9766. (SCI)
• Chuang WY, Chen CC, Yu WH, Yeh CJ, Chang SH, Ueng SH, Wang TH, Hsueh C, Kuo CF, Yeh CY. Identification of nodal micrometastasis in colorectal cancer using deep learning on annotation-free whole-slide images. Mod Pathol 2021; 34(10): 1901-1911. (SCI)
• Chuang WC, Ueng SH, Chuang WY, Chan KC. Nodular mass-A case of auricular schwannoma. Ear Nose Throat J 2024; 103(9): 535-537. (SCI)
• Huang RW, Anggelia MR, Chuang WY, Hsieh YH, Cheng HY, Lin CH. The Effect of Narrow-Band Ultraviolet B Irradiation on the Vascularized Composite Allotransplantation Rat Model. Ann Plast Surg 2022; 88(1s Suppl 1): S22-S26. (SCI)
• Hang JF, Yuan CT, Chang KC, Wang RC, Chen BJ, Hsieh PP, Huang WT, Chuang WY, Chen TW, Yeh YC, Lin SY, Hsiao CH, Chou SC, Tseng CE, Pan ST, Chang SL, Chuang SS. Targeted Next-generation Sequencing Reveals a Wide Morphologic and Immunophenotypic Spectrum of Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma. Am J Surg Pathol 2022; 46(9): 1207-1218. (SCI)
• Lim JQ, Huang D, Chan JY, Laurensia Y, Wong EKY, Cheah DMZ, Chia BKH, Chuang WY, Kuo MC, Su YJ, Cai QQ, Feng Y, Rao H, Feng LN, Wei PP, Chen JR, Han BW, Lin GW, Cai J, Fang Y, Tan J, Hong H, Liu Y, Zhang F, Li W, Poon MLM, Ng SB, Jeyasekharan A, Ha JCH, Khoo LP, Chin ST, Pang WL, Kee R, Cheng CL, Grigoropoulos NF, Tang T, Tao M, Farid M, Puan KJ, Xiong J, Zhao WL, Khor CC, Hwang W, Kim WS, Campo E, Tan P, Teh BT, Chng WJ, Rötzschke O, Tousseyn T, Huang HQ, Rozen S, Lim ST, Shih LY, Bei JX, Ong CK. A genomic-augmented multivariate prognostic model for the survival of Natural-killer/T-cell lymphoma patients from an international cohort. Am J Hematol 2022; 97(9): 1159-1169. (SCI)
• Chuang WY, Yu WH, Lee YC, Zhang QY, Chang H, Shih LY, Yeh CJ, Lin SMT, Chang SH, Ueng SH, Wang TH, Hsueh C, Kuo CF, Chuang SS, Yeh CY. Deep learning-based nuclear morphometry reveals an independent prognostic factor in mantle cell lymphoma. Am J Pathol 2022; 192(12): 1763-1778. (SCI)
• Wang RC, Chen BJ, Yuan CT, Ho CH, Chuang WY, Chen SW, Chang JH, Yu WH, Chuang SS. The spectrum of intestinal mature T- and NK-cell neoplasms in a tertiary center in Taiwan with a high frequency of perforation. Pathol Res Pract 2022; 240: 154184. (SCI)
• Lin CH, Anggelia MR, Cheng HY, Hsieh YH, Chuang WY, Yang HY, Lin CH. The intragraft vascularized bone marrow induces secondary donor-specific mystacial pad allograft tolerance. Front Immunol 2022; 13: 1059271. (SCI)
• Kuo MC, Chuang WY, Chang H, Lin TH, Wu JH, Lin TL, Ou CW, Hung YS, Huang TY, Huang YJ, Wang PN, Shih LY. Comparison of Clinical and Molecular Features Between Patients With Essential Thrombocythemia and Early/Prefibrotic Primary Myelofibrosis Presenting With Thrombocytosis in Taiwan. Am J Clin Pathol 2023; 159(5): 474-483. (SCI)
• Chen CC, Chen CY, Yeh CT, Liu YT, Leu YL, Chuang WY, Shih YH, Chou LF, Shieh TM, Wang TH. Corylin Attenuates CCl4-Induced Liver Fibrosis in Mice by Regulating the GAS6/AXL Signaling Pathway in Hepatic Stellate Cells. Int J Mol Sci 2023; 24(23): 16936. (SCI)
• Chen BJ, Hsieh TH, Yuan CT, Wang RC, Yang CF, Chuang WY, Su YZ, Ho CH, Lin CH, Chuang SS. Clinicopathological and genetic landscape of plasmablastic lymphoma in Taiwan. Pathol Res Pract 2024; 253: 155059. (SCI)
• Chen NC, Chang H, Kuo MC, Lin TL, Shih LY, Chuang WY, Kao HW. Predictive model for treatment outcomes of peripheral T-cell lymphoma, not otherwise specified, in Taiwanese patients. J Formos Med Assoc 2024; 123(2): 188-197. (SCI)
• Chuang WY*, Lee CW*, Fan WL*, Liu TT, Lin ZH, Wang KC, Huang PJ, Yeh YM, Lin TC. Wnt-5a-Receptor Tyrosine Kinase-Like Orphan Receptor 2 Signaling Provokes Metastatic Colonization and Angiogenesis in Renal Cell Carcinoma, and the Axis Activation Is Suppressed by Prunetin. Am J Pathol 2024; 194(10): 1967-1985. (*contributed equally) (SCI)
• Chuang WY, Chang H, Shih LY, Lin TC, Yeh CJ, Ueng SH, Kuo MC, Kao HW, Liu H, Chang ST, Lee CL, Huang KP, Wang TH, Wan YL, Yu JS, Hsueh C, Chuang SS. Identification of CD5/SOX11 double-negative pleomorphic mantle cell lymphoma. Virchows Arch 2024; 485(2): 323-334. (SCI)
• Chuang PW, Chuang WY, Lee TJ, Chang PH, Chen YW, Fu CH. Outcome Analysis of Solitary Extramedullary Plasmacytoma in the Head and Neck: A Clinical Perspective. Head Neck 2024 Nov 18 (Epub ahead of print) (SCI)

B.Presentations

• Chuang WY. Experience in digital pathology: practice and research, 19th Annual Meeting of Japanese Society of Digital Pathology, Japan, 2021. (Oral Presentation)
• Chuang WY. Beyond the algorithm: creating AI solutions that pathologists need, The 13th Symposium on the Industry-Government-Academia Collaborative Forefront Cancer Genome, Japan, 2024. (Oral Presentation)